Hamzah Bakouni, a postdoctoral trainee, and his colleagues in our laboratory, recently published an article in the Journal of Addiction Medicine in collaboration with Lexie Haquet, M Eugenia Socias, Bernard Le Foll, Ron Lim, Keith Ahamad, and under the supervision of Dr. Didier Jutras-Aswad.
This article focused on describing the titration patterns of two commonly used replacement treatments in prescription-type opioid use disorder: methadone and buprenorphine-naloxone, while describing their impact on different treatment outcomes.
By studying 167 participants aged 18-64 years old with prescription-type opioid use disorder who received replacement treatment, this study concluded that specific parameters of methadone titration were associated with treatment outcomes and may help in personalizing treatment schedules. Sustained methadone dose titration, when indicated, may help increase retention in treatment, whereas faster dose titration for methadone may help decrease opioid use by individuals with opioid use disorder.
To read the full article: http://tinyurl.com/3zpxj68b