The use of non-therapeutic cannabis in the context of epilepsy and its health implications
The use of cannabis among people with epilepsy is a growing concern. Approximately 50% of individuals with epilepsy consume cannabis non-therapeutically and without the supervision of a healthcare professional. The majority of scientific studies suggest that the anti-seizure effects attributed to cannabis are linked to CBD at very high doses, with robust evidence to date primarily involving pediatric populations with very specific epileptic syndromes. While some uncertain data suggest that THC might influence the intensity and frequency of seizures in certain populations, the supporting evidence remains limited, as most studies have been conducted on products containing predominantly CBD and very little THC. Furthermore, some studies mention that the neurocognitive negative impacts of cannabis are primarily due to THC.
Given the significant number of people with epilepsy who have cognitive and mental health issues, or who are predisposed to developing them, it is necessary to evaluate the prevalence and patterns of non-medical cannabis use, as well as its correlational association with cognitive and mental health in the context of epilepsy. The results of this research will have significant implications for the clinical management of patients and public health policies.
In collaboration with the research laboratory of Dr. Dang Khoa Nguyen, a neuro-epileptologist at CHUM, our research team is conducting a study aimed at providing evidence on the effects of non-therapeutic cannabis use on mental and cognitive health in the context of epilepsy. This study uses surveys and neuropsychological assessments. Our preliminary results show that, over the past 12 months, 42% of men and 19% of women have consumed non-medical cannabis. Among them, 72% reported consuming cannabis containing exclusively THC, more THC than CBD, or equal amounts of THC and CBD. Furthermore, respondents felt poorly or not at all informed about the benefits (72%) and risks (71%) to their health, highlighting the need to address the current knowledge gaps surrounding non-medical cannabis use among people with epilepsy.
This study will enable concerned individuals to make informed choices, considering the potential risks and benefits of non-medical cannabis use.
The advancements of our research will be published on our website, in the “News” section.
Article by Daphné Citherlet
