Learn more about:



Participants wanted :

Men and women consuming opioids and wishing to access a substitution treatment.

What is OPTIMA?:

This randomized clinical trial (NCT03033732) consisted of comparing the effectiveness of two models of care for the management of opioid use. The first is methadone treatment and the second is buprenorphine/naloxone treatment.

Your role :

  • Attend follow-up visits every two weeks during 24-28 weeks
  • Fill out a questionnaire

You were not admissible if:

  • You have a contraindication to the medication used for this study
  • You are pregnant, breastfeeding or if you plan a pregnancy during the study
  • You are currently on agonist treatment (methadone or buprenorphine/naloxone)

To participate in one of our ongoing studies, please consult our directory.

Read the scientific article published in The American  Journal of Psychiatry

To see our knowledge transfer initiatives, please consult The OPTIMA Trial.

étude optima

If you have questions, you can read our FAQ sheet or contact us.


CHUM Research Center (CRCHUM)

900 St-Denis St., 4th & 5th floor,

Montreal (QC) H2X0A9

Phone: 514-890-8000 #30933
Email: labo.jutras.aswad@gmail.com

To contact the media relations team: andree-anne.toussaint.chum@ssss.gouv.qc.ca

Myths and realities of a clinical research study

Didier Jutras-Aswad

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Thank you to the funding agencies

*People wishing to participate in one of the studies or who have questions about them can contact the lab. People who wish to obtain addiction and/or mental health care or services can contact the addiction rehabilitation center or the psychosocial center in their region. They can also call emergency services if their condition requires it.